CRYSTAL-STRUCTURES OF B-FORM DNA-RNA CHIMERS COMPLEXED WITH DISTAMYCIN

被引：75

作者：

CHEN, X ^{[1
]}

RAMAKRISHNAN, B ^{[1
]}

SUNDARALINGAM, M ^{[1
]}

机构：

[1] OHIO STATE UNIV,DEPT BIOCHEM,COLUMBUS,OH

来源：

NATURE STRUCTURAL BIOLOGY | 1995年 / 2卷 / 09期

关键词：

D O I：

10.1038/nsb0995-733

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two DNA-RNA chimers, complexed with DNA minor groove bind ng drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.

引用

页码：733 / 735

页数：3

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