CONFIGURATION OF LATENT VARICELLA-ZOSTER VIRUS-DNA

被引:51
作者
CLARKE, P [1 ]
BEER, T [1 ]
COHRS, R [1 ]
GILDEN, DH [1 ]
机构
[1] UNIV COLORADO,HLTH SCI CTR,DEPT MICROBIOL,DENVER,CO 80262
关键词
D O I
10.1128/JVI.69.12.8151-8154.1995
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The configuration of latent varicella-zoster virus (VZV) DNA was analyzed by PCR. Template DNA for both internal and terminal VZV primers was present in a 1:1 ratio in ganglionic DNA, compared with a 15:1 ratio in DNA extracted from VZV virions, indicating that the VZV genomic termini are adjacent in latently infected human ganglia.
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页码:8151 / 8154
页数:4
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