TOTAL PARENTERAL-NUTRITION AND NUTRITIONAL ASSESSMENT IN LEUKEMIC CHILDREN UNDERGOING BONE-MARROW TRANSPLANTATION

被引：39

作者：

UDERZO, C ^{[1
]}

ROVELLI, A ^{[1
]}

BONOMI, M ^{[1
]}

FOMIA, L ^{[1
]}

PIROVANO, L ^{[1
]}

MASERA, G ^{[1
]}

机构：

[1] SAN GERARDO HOSP, DEPT LAB MED, I-20052 MONZA, ITALY

来源：

EUROPEAN JOURNAL OF CANCER | 1991年 / 27卷 / 06期

关键词：

D O I：

10.1016/0277-5379(91)90183-E

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The aggressive radiotherapy and chemotherapy used in conditioning regimens for children with leukaemia undergoing bone marrow transplantation (BMT) cause a severe catabolic state. Total parenteral nutrition (TPN) is indispensable in the management of these patients. 25 children with leukaemia undergoing BMT were studied to evaluate the efficacy of TPN and the value of anthropometric parameters and biochemical variables (albumin, retinol-binding protein and prealbumin) in monitoring nutritional status in the critical post-BMT phase. The complications of TPN were mainly metabolic, generally mild and easily controlled. The hyperalimentation solution and infusion line were not responsible for infection in any patient. The marked variations in anthropometric parameters and albumin expected in such patients were not observed in our children due to the nutritional support given. Prealbumin and retinol-binding protein showed statistically significant, positive variations (P < 0.01), thus proving sensitive indices of the response to nutritional repletion.

引用

页码：758 / 762

页数：5

共 32 条

[1]

Aker SN, 1990, NUTR MANAGEMENT CANC, P199

[2]

APPELBAUM FR, 1988, SEMIN HEMATOL, V25, P16

[3] NUTRITIONAL ASSESSMENT - A COMPARISON OF CLINICAL JUDGMENT AND OBJECTIVE MEASUREMENTS [J].