Gastroesophageal reflux and idiopathic pulmonary fibrosis: A long term relationship

被引：5
作者：
Gnanapandithan, Karthik [1 ,2 ]
Popkin, Joel H. [3 ,4 ]
Devadoss, Ramprakash [5 ]
Martin, Kevin [4 ,6 ]
机构：
[1] Yale New Haven Med Ctr, Dept Internal Med, 20 York St, New Haven, CT 06511 USA
[2] Yale Univ, Sch Med, 20 York St, New Haven, CT 06511 USA
[3] St Vincent Hosp, Dept Med, Worcester, MA 01604 USA
[4] Reliant Med Grp, Worcester, MA USA
[5] St Vincent Hosp, Dept Internal Med, Worcester, MA 01604 USA
[6] St Vincent Hosp, Pulm Div, Worcester, MA 01604 USA
来源：
RESPIRATORY MEDICINE CASE REPORTS | 2016年 / 17卷
关键词：
Gastroesophageal reflux; Idiopathic pulmonary fibrosis; Pulmonary fibrosis; Acid reflux; Proton pump inhibitor; Fundoplication;
D O I：
10.1016/j.rmcr.2016.01.002
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Idiopathic pulmonary fibrosis (IPF) is a dreaded disease of uncertain etiology and no available cure. It is still unclear if a causal relationship exists between gastro-esophageal reflux (GER) and IPF, but studies have shown an increased prevalence of acid reflux in patients with IPF. We describe a patient with achalasia and GER who went on to develop IPF. She underwent a rapidly worsening course punctuated by acute exacerbations of IPF, despite best efforts to manage the acid GER. We also reviewed the literature on the role of GER in the etiology and progression of IPF and the impact of antireflux measures on its course. (C) 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
引用
收藏
页码：40 / 43
页数：4
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