EVALUATION OF IN-VITRO ANTI-OXIDANT ACTIVITY OF SOME SYNTHESIZED NOVEL L-AiRGININE ANALOGUES

A series of novel L-arginine analogues were synthesized and screened for in-vitro anti-oxidant activity by Nitric oxide (NO) scavenging and 1-1-diphenyl-2-picrylhydrazyl (DPPH) scavenging methods. The purity of the synthesized compounds has been characterized by various analytical techniques such as UV, FTIR and TLC. The synthesized compounds were evaluated for invitro anti-oxidant activity by NO scavenging and DPPH scavenging methods. The study concluded that the compounds4, 5, 6, 7, 8, 10, 11 exhibited very significant anti-oxidant action in NO scavenging method and compounds 4, 6, 7, 8, 10, 11 has exhibited significant anti-oxidant activity in DPPH scavenging method when compared with that of the standard Ascorbic acid.