REACTIONS OF ORGANIC-ANIONS .193. VICARIOUS NUCLEOPHILIC-SUBSTITUTION OF HYDROGEN IN PYRIDAZINES

被引：14

作者：

OSTROWICZ, A

BALONIAK, S

MAKOSZA, M

RYKOWSKI, A

机构：

[1] POLISH ACAD SCI,INST ORGAN CHEM,PL-01224 WARSAW,POLAND

[2] MED ACAD POZNAN,DEPT ORGAN CHEM,PL-60780 POZNAN,POLAND

[3] AGR & TEACHERS UNIV,INST CHEM,PL-08110 SIEDLCE,POLAND

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(00)61286-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyridazines, 3-pyridazinones and 3,6-pyridazinediones readily undergo vicarious nucleophilic substitution of hydrogen (VNS) with carbanion of chloromethyl p-tolyl sulfone to form new carbon-carbon bonds. The reaction offers a novel approach to the synthesis of functionalized pyridazine derivatives.

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收藏

页码：4787 / 4790

页数：4

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