FURTHER EVIDENCE FOR BOTH FUNCTIONAL AND STRUCTURAL MICROCOMPARTMENTATION WITHIN THE MEMBRANES OF 2 ASSOCIATED ORGANELLES, MITOCHONDRION AND ENDOPLASMIC-RETICULUM

被引：9

作者：

GASNIER, F ^{[1
]}

ARDAIL, D ^{[1
]}

FEBVAY, G ^{[1
]}

SIMONOT, C ^{[1
]}

LERME, F ^{[1
]}

GUILLAUD, J ^{[1
]}

LOUISOT, P ^{[1
]}

GATEAUROESCH, O ^{[1
]}

机构：

[1] INRA,INSA,F-69921 VILLEURBANNE,FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 195卷 / 03期

关键词：

D O I：

10.1006/bbrc.1993.2194

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We previously demonstrated that the translocation of phospholipids between the mitochondrion and the endoplasmic reticulum occurs via highly specialized membrane microdomains of both organelles that are in situ closely associated. As understanding of the interactions between both organelles requires characterization of the translocation sites organization, we first analysed the amino acid compositions of these sites. Using principal component analysis, we have shown that the translocation sites exhibit characteristic patterns when compared with the membranes from which they are derived. The results are discussed in terms of both functional and structural microcompartmentation within the membranes of mitochondria and endoplasmic reticulum. © 1993 Academic Press, Inc.

引用

页码：1365 / 1370

页数：6

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[4]

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