GLYCEROPHOSPHOLIPIDS AND CHOLESTEROL COMPOSITION OF BILE IN BILE-FISTULA RATS TREATED WITH MONENSIN

被引:14
作者
CASU, A
CAMOGLIANO, L
机构
[1] Institute of General Pathology, University of Genoa, Genoa
关键词
Bile; Cholesterol; Glycerophospholipid; Membrane; Monensin;
D O I
10.1016/0005-2760(90)90117-G
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Data regarding the action of monensin on the concentrations of glycerophospholipids and cholesterol in bile of rats subjected to total biliary diversion for 3 h are reported. After monensin their concentration in bile drops significantly in the first 60 min collections with respect to the control. Differences seem to be produced between the rates of transport to the bile of glycerophospholipids and cholesterol, not sufficiently explained by the inhibition of bile salt uptake determined by monensin at the sinusoidal pole of the hepatocyte. © 1990.
引用
收藏
页码:113 / 115
页数:3
相关论文
共 26 条
[1]   INHIBITION OF BILIARY TAUROCHOLATE EXCRETION DURING MENADIONE METABOLISM IN PERFUSED RAT-LIVER [J].
AKERBOOM, T ;
BULTMANN, T ;
SIES, H .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1988, 263 (01) :10-18
[2]  
ANANTHANARAYANA.M, 1988, J BIOL CHEM, V263, P8270
[3]  
BOWMAN RE, 1962, CLIN CHEM, V8, P302
[4]   BILE-ACIDS IN BILE AFTER MONENSIN TREATMENT [J].
CAMOGLIANO, L ;
CASU, A .
EXPERIMENTAL PATHOLOGY, 1989, 36 (01) :37-41
[5]  
CASU A, 1976, ITAL J BIOCHEM, V25, P390
[6]  
CASU A, 1984, ITAL J BIOCHEM, V34, P1
[7]   BIOCHEMISTRY OF BILE SECRETION [J].
COLEMAN, R .
BIOCHEMICAL JOURNAL, 1987, 244 (02) :249-261
[8]  
FINK JA, 1985, BIOCHEM ARCH, V1, P37
[9]  
FOLCH J, 1957, J BIOL CHEM, V226, P497
[10]  
HANOVER JA, 1988, PROTEIN TRANSFER ORG, P412