A MODIFICATION OF THE REDISTRIBUTION TO THE RIGHT ALGORITHM USING DISEASE MARKERS

被引：34

作者：

MALANI, HM

机构：

[1] School of Public Health, University of California, Berkeley

来源：

BIOMETRIKA | 1995年 / 82卷 / 03期

关键词：

CENSORED OBSERVATIONS; INFORMATIVE CENSORING; KAPLAN-MEIER ESTIMATOR; LOG-RANK TEST; PROPORTIONAL HAZARDS MODEL; SURVIVAL ANALYSIS;

D O I：

10.1093/biomet/82.3.515

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Disease markers are time-dependent covariates which describe progression towards development of disease. Traditional methods in survival analysis do not make use of available data on these markers to recover additional information from censored individuals. Using a heuristic modification of the redistribution to the right algorithm (Efron, 1967), a new approach for recovering information for censored individuals using disease markers is proposed. Additionally, the statistical properties of the proposed method are examined. There are two possible advantages to this modification: (i) bias reduction when censoring is informative, and (ii) an increase in efficiency in the case of truly noninformative censoring.

引用

页码：515 / 526

页数：12

共 12 条

[1] COX REGRESSION-MODEL FOR COUNTING-PROCESSES - A LARGE SAMPLE STUDY [J].