RETINOBLASTOMA IN THE 1ST YEAR OF LIFE

被引:18
作者
ABRAMSON, DH
SERVODIDIO, CA
机构
[1] Department of Ophthalmology, New-York Hospital-Cornell Medical Center, New York, NY
来源
OPHTHALMIC PAEDIATRICS AND GENETICS | 1992年 / 13卷 / 04期
关键词
RETINOBLASTOMA; EYE; CANCER; RADIATION; 2ND TUMORS; NEWBORN;
D O I
10.3109/13816819209105167
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Children diagnosed with retinoblastoma in the first year of life present with differences in laterality, stage, signs, symptoms, and respond differently to treatments when compared to older children. Of those children diagnosed in the first year of life (between 1958 and 1983 inclusive), 280 were bilateral and 121 were unilateral, the most common stage of diagnosis (for unilateral and bilateral) was Group V, and children were affected equally by sex. Children examined in the first three months of life were more often seen because of a positive family history of retinoblastoma, rather than leukocoria. Children who were treated in the first year of life frequently develop second nonocular tumors because they harbor the germinal mutation and receive radiation.
引用
收藏
页码:191 / 203
页数:13
相关论文
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