SUBSTITUTING AN ALPHA-HELIX SWITCHES THE SEQUENCE-SPECIFIC DNA INTERACTIONS OF A REPRESSOR

被引：123

作者：

WHARTON, RP ^{[1
]}

BROWN, EL ^{[1
]}

PTASHNE, M ^{[1
]}

机构：

[1] GENET INST,BOSTON,MA 02115

来源：

CELL | 1984年 / 38卷 / 02期

关键词：

D O I：

10.1016/0092-8674(84)90491-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：361 / 369

页数：9

共 34 条

[1] VECTORS BEARING A HYBRID TRP-LAC PROMOTER USEFUL FOR REGULATED EXPRESSION OF CLONED GENES IN ESCHERICHIA-COLI [J].

AMANN, E ;

BROSIUS, J ;

PTASHNE, M .

GENE, 1983, 25 (2-3) :167-178

[2] COCRYSTALS OF THE DNA-BINDING DOMAIN OF PHAGE-434 REPRESSOR AND A SYNTHETIC PHAGE 434 OPERATOR [J].

ANDERSON, J ;

PTASHNE, M ;

HARRISON, SC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (05) :1307-1311

[3] STRUCTURE OF THE CRO REPRESSOR FROM BACTERIOPHAGE-LAMBDA AND ITS INTERACTION WITH DNA [J].

ANDERSON, WF ;

OHLENDORF, DH ;

TAKEDA, Y ;

MATTHEWS, BW .

NATURE, 1981, 290 (5809) :754-758

[4] DEOXYNUCLEOSIDE PHOSPHORAMIDITES - A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS [J].

BEAUCAGE, SL ;

CARUTHERS, MH .

TETRAHEDRON LETTERS, 1981, 22 (20) :1859-1862

[5] MECHANISM OF ACTION OF THE LEXA GENE-PRODUCT [J].

BRENT, R ;

PTASHNE, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (07) :4204-4208

[6]

Comstock L. J., 1982, PROMOTERS STRUCTURE, P462

[7] SITE-SPECIFIC MUTAGENESIS USING SYNTHETIC OLIGODEOXYRIBONUCLEOTIDE PRIMERS .2. INVITRO SELECTION OF MUTANT-DNA [J].

GILLAM, S ;

SMITH, M .

GENE, 1979, 8 (01) :99-106

[8] NUCLEOTIDE-SEQUENCE OF THE CRO-CII-OOP REGION OF BACTERIOPHAGE-434DNA [J].

GROSSCHEDL, R ;

SCHWARZ, E .

NUCLEIC ACIDS RESEARCH, 1979, 6 (03) :867-881

[9] MUTATIONS IN LAMBDA-REPRESSORS AMINO-TERMINAL DOMAIN - IMPLICATIONS FOR PROTEIN STABILITY AND DNA-BINDING [J].

HECHT, MH ;

NELSON, HCM ;

SAUER, RT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (09) :2676-2680

[10] MECHANISM OF ACTION OF CRO-PROTEIN OF BACTERIOPHAGE-LAMBDA [J].

JOHNSON, A ;

MEYER, BJ ;

PTASHNE, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (04) :1783-1787

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