Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

被引：5

作者：

English, Jane A. ^{[1
,2
]}

Scaife, Caitriona ^{[2
]}

Harauma, Akiko ^{[3
]}

Focking, Melanie ^{[1
]}

Wynne, Kieran ^{[2
]}

Cagney, Gerard ^{[2
]}

Moriguchi, Toru ^{[3
]}

Cotter, David R. ^{[1
]}

机构：

[1] Royal Coll Surgeons Ireland, ERC Beaumont Hosp, Dept Psychiat, Dublin, Ireland

[2] Univ Coll Dublin, UCD Conway Inst Biomol & Biomed Res, Sch Med & Med Sci, Proteome Res Ctr, Dublin, Ireland

[3] Azabu Univ, Dept Food & Life Sci, Sagamihara, Kanagawa, Japan

来源：

DATA IN BRIEF | 2016年 / 7卷

基金：

爱尔兰科学基金会;

关键词：

Mouse; Brain; Hippocampus; Proteins; Proteomics; Mass spectrometry; Omega-3; deficiency;

D O I：

10.1016/j.dib.2015.12.057

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/40).

引用

页码：341 / 343

页数：3

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