Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only

被引：12
作者：
Jobsen, Jan J. [1 ]
ten Cate, Lambert Naudin [2 ]
Lybeert, Marnix L. M. [3 ]
Scholten, Astrid [4 ]
van der Steen-Banasik, Elzbieta M. [5 ,6 ,7 ]
van der Palen, Job
Kroese, Marika C. Stenfert [8 ]
Slot, Annerie [9 ]
Schutter, Eltjo M. J. [10 ]
Siesling, Sabine [11 ]
机构：
[1] Med Spectrum Twente, Dept Radiat Oncol, Haaksbergerstr 55, NL-7513 ER Enschede, Netherlands
[2] Lab Pathol Oost Nederland, NL-7512 ER Enschede, Netherlands
[3] Catharina Hosp, Dept Radiat Oncol, Eindhoven, Netherlands
[4] Leiden Univ, Med Ctr, Dept Clin Oncol, NL-2333 ZA Leiden, Netherlands
[5] Arnhem Radiotherapeut Inst, Arnhem, Netherlands
[6] Univ Twente, Fac Behav Sci, Dept Res Methodol Measurement & Data Anal, NL-7500 AE Enschede, Netherlands
[7] Med Spectrum Twente, Dept Clin Epidemiol, NL-7513 ER Enschede, Netherlands
[8] Radiotherapy Inst Steden Omstreken, Deventer, Netherlands
[9] Radiotherapy Inst Friesland, Leeuwarden, Netherlands
[10] Med Spectrum Twente, Dept Obstet & Gynaecol, NL-7513 ER Enschede, Netherlands
[11] Comprehens Canc Ctr North East, Enschede, Netherlands
来源：
OBSTETRICS AND GYNECOLOGY INTERNATIONAL | 2011年 / 2011卷
关键词：
D O I：
10.1155/2011/962518
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P =.0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P =.3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa.
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页数：7
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