FORMULATION OPTIMIZATION OF A HYDROCOLLOID DRESSING

被引：5
作者：
NANGIA, A
LAM, F
HUNG, CT
机构：
[1] UNIV OTAGO, DEPT PHARM, DUNEDIN, NEW ZEALAND
[2] UNIV OTAGO, DEPT MATH & STAT, DUNEDIN, NEW ZEALAND
[3] ZENITH TECHNOL CO LTD, DUNEDIN, NEW ZEALAND
来源：
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1990年 / 16卷 / 14期
关键词：
D O I：
10.3109/03639049009023643
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A methodology of mixture experiments has been applied to the formulation of a multicomponent hydrocolloid dressing. Using an extreme vertices statistical design, a semi-occlusive dressing composed of dextran, phospholipid, glycerol and sodium lauryl sulphate has been formulated, which checks evaporative water loss (EWL) from the excised wound surface of rats to an optimum level. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：2109 / 2123
页数：15
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