MUCOEPIDERMOID CARCINOMA OF THE PANCREAS - REPORT OF A CASE

被引:29
作者
ONODA, N
KANG, SM
SUGANO, S
YAMASHITA, Y
CHUNG, YS
SOWA, M
机构
[1] First Department of Surgery, Osaka City University Medical School, Osaka, 545, 1-5-7 Asahi-machi, Abeno-ku
[2] Department of Surgery, Tadaoka Municipal Hospital, Osaka, 595, 1-3-7 Tadaoka-kita, Tadaoka-cho, Senboku-gun
来源
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY | 1995年 / 25卷 / 09期
关键词
PANCREATIC TUMOR; MUCOEPIDERMOID CARCINOMA; PANCREATIC CANCER-ASSOCIATED ANTIGEN; IMMUNOHISTOCHEMICAL STAINING;
D O I
10.1007/BF00311465
中图分类号
R61 [外科手术学];
学科分类号
摘要
We present herein the case of a 64-year-old man diagnosed as having a mucoepidermoid carcinoma of the pancreas. The tumor originated in the tail of the pancreas and invaded the spleen, left adrenal gland, left kidney, and transverse colon. Liver and peritoneal metastases were also noted. Despite surgical treatment and adjuvant chemotherapy, the disease progressed rapidly and the patient died of cachexia 4 months after his initial diagnosis. Mucoepidermoid carcinoma of the pancreas is a rare entity, and is believed to be a form of adenosquamous carcinoma known as adenoacanthoma. However, in this patient, no differentiated squamous cell component could be detected. In fact, the tumor was composed of mucin-producing cells, epidermoid cells, and intermediate cells. Immunohistochemical staining for the carcinoembryonic antigen, CA19-9, and SPan-1 demonstrated a production of cancerous mucin in the epidermoid cells, suggesting that mucoepidermoid carcinoma may arise from the squamoid metaplasia of an adenocarcinoma.
引用
收藏
页码:843 / 847
页数:5
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