METHOTREXATE FOR THE TREATMENT OF SEVERE MUCOCUTANEOUS LUPUS-ERYTHEMATOSUS

被引：24

作者：

BOTTOMLEY, WW

GOODFIELD, M

机构：

[1] Department of Dermatology, Leeds General Infirmary, Leeds LS1 3EX, Great George Street

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1995年 / 133卷 / 02期

关键词：

D O I：

10.1111/j.1365-2133.1995.tb02637.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report three women with severe, chronic mucocutaneous lupus erythematosus who showed a significant improvement during oral methotrexate therapy; the improvement was sustained after the drug was discontinued. Their disease had previously been refractory to a wide range of conventional systemic immunosuppressive therapies. Other treatments were progressively withdrawn, and control was maintained, for a variable length of time, with methotrexate alone, or with a small dose of prednisolone.

引用

页码：311 / 314

页数：4

共 12 条

[1]

ALARCON GS, 1990, ARTHRITIS RHEUM, V33, P1156

[2]

CHANG DM, 1992, J RHEUMATOL, V19, P1678

[3]

GARCIA MG, 1993, MED CLIN-BARCELONA, V101, P361

[4]

HUGHES GRV, 1994, J ROY COLL PHYS LOND, V28, P260

[5]

MIESCHER P A, 1965, Semin Hematol, V2, P1

[6]

NORRIS DA, 1977, J LAB CLIN MED, V90, P569

[7] THE USE OF METHOTREXATE IN STEROID-RESISTANT SYSTEMIC LUPUS-ERYTHEMATOSUS [J].

ROTHENBERG, RJ ;

GRAZIANO, FM ;

GRANDONE, JT ;

GOLDBERG, JW ;

BJARNASON, DF ;

FINESILVER, AG .

ARTHRITIS AND RHEUMATISM, 1988, 31 (05) :612-615

[8]

SPERLING RI, 1990, ARTHRITIS RHEUM, V33, P1149

[9] SPECIAL ARTICLE - THE 1982 REVISED CRITERIA FOR THE CLASSIFICATION OF SYSTEMIC LUPUS-ERYTHEMATOSUS [J].

TAN, EM ;

COHEN, AS ;

FRIES, JF ;

MASI, AT ;

MCSHANE, DJ ;

ROTHFIELD, NF ;

SCHALLER, JG ;

TALAL, N ;

WINCHESTER, RJ .

ARTHRITIS AND RHEUMATISM, 1982, 25 (11) :1271-1277

[10] LONG-TERM PROSPECTIVE-STUDY OF METHOTREXATE IN THE TREATMENT OF RHEUMATOID-ARTHRITIS - 84-MONTH UPDATE [J].

WEINBLATT, ME ;

WEISSMAN, BN ;

HOLDSWORTH, DE ;

FRASER, PA ;

MAIER, AL ;

FALCHUK, KR ;

COBLYN, JS .

ARTHRITIS AND RHEUMATISM, 1992, 35 (02) :129-137

← 1 2 →