SYNTHESIS OF 8-METHYL-TRANS,TRANS-CYCLODECA-3-7-DIEN-1-BETA-OL AND BIOTRANSFORMATION INTO 4A-BETA-METHYL-1,2,3,4,4A,5,6,7,8,8A-ALPHA-DECAHYDRONAPHTHALENE-1,7-BETA-DIOL BY CICHORIUM-INTYBUS

被引：6

作者：

PIET, DP ^{[1
]}

FRANSSEN, MCR ^{[1
]}

DEGROOT, A ^{[1
]}

机构：

[1] AGR UNIV WAGENINGEN,DEPT ORGAN CHEM,6703 HB WAGENINGEN,NETHERLANDS

来源：

TETRAHEDRON | 1994年 / 50卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(01)81115-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The biotransformation of 8-methyl-trans,trans-cyclodeca-3,7-dien-1 beta-ol (6) into trans-decaline 7 by a suspension of fresh chicory root (Cichorium intybus) was investigated. In this paper, the synthesis of 6 as well as its enzymatic transformation into 7, is presented. A transannular cyclization mechanism of the enzymatically acquired products is proposed.

引用

页码：3169 / 3176

页数：8

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