LOCATION OF UNSATURATED POSITIONS IN PHOSPHATIDYL CHOLINES BY CONSECUTIVE-REACTION MONITORING

被引：15

作者：

BRYANT, DK ^{[1
]}

ORLANDO, R ^{[1
]}

机构：

[1] UNIV MARYLAND,DEPT CHEM & BIOCHEM,CATONSVILLE,MD 21228

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1991年 / 5卷 / 03期

关键词：

D O I：

10.1002/rcm.1290050307

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Consecutive-reaction monitoring (MS3) of negative ions has been shown to be useful in locating double bonds in the fatty acid ester groups of individual phosphatidyl cholines present in complex mixtures. This information is derived from charge-remote fragmentations of carboxylate anions produced by collisional activation of the [M-CH3]- precursor ions from phosphatidyl cholines. The added selectivity of this technique increases the sensitivity, relative to that of tandem mass spectrometry (MS2), such that only 3 pmol are needed to perform this analysis.

引用

页码：124 / 127

页数：4

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