Data regarding the standards of bronchoscopic practice in Cairo hospitals, where the main bulk of the procedures in Egypt takes place, are lacking and have not been studied. A questionnaire-based survey was conducted aiming to assess the present status of performing flexible bronchoscopy (FB) and the extent of variations in chest physicians practice. All bronchoscopists performing FB were identified. A questionnaire consisting of 50 questions covering different aspects of bronchoscopy practice was distributed. Seventy-five bronchoscopists out of 87 (86%) returned the questionnaire and they had performed a total of 5994 bronchoscopies in the preceding year. The majority of practice is limited only to around 55% of bronchoscopists. The responders sometimes (20%) or never (3%) take proper precautions while performing FB in suspected airborne infections. Only 15% of bronchoscopists obtained a signed patient consent before bronchoscopy. Fifty-three (75%) of bronchoscopists gave benzodiazepine sedation and only 30 (42%) record availability of sedative antagonists. Sixty-six (88%) responders prescribed atropine. All bronchoscopies were performed under topical lidocaine. Seventy-six percent of physicians monitored oximetry and 15% never monitored oximetry during the procedures. Marked variance was noted in sampling routines of suspected tumors. Only 21 (28%) and 47 (63%) of responders had performed transbronchial needle aspiration or lung biopsy over the preceding year, respectively. The mortality rate of FB was 0.01% with a 3% incidence of complications. We concluded from the presented data that bronchoscopic practice in Cairo is not standardized, and there is a need for national database, guidelines, and training programs for bronchoscopy practice.