SWITCHING KINETIC MECHANISM AND PUTATIVE PROTON DONOR BY DIRECTED MUTAGENESIS OF GLUTATHIONE-REDUCTASE

被引：66
作者：
BERRY, A [1 ]
SCRUTTON, NS [1 ]
PERHAM, RN [1 ]
机构：
[1] UNIV CAMBRIDGE,DEPT BIOCHEM,TENNIS COURT RD,CAMBRIDGE CB2 1QW,ENGLAND
来源：
BIOCHEMISTRY | 1989年 / 28卷 / 03期
关键词：
D O I：
10.1021/bi00429a047
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：1264 / 1269
页数：6
相关论文
共 33 条
[1]   BUFFER GRADIENT GELS AND S-35 LABEL AS AN AID TO RAPID DNA-SEQUENCE DETERMINATION [J].
BIGGIN, MD ;
GIBSON, TJ ;
HONG, GF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13) :3963-3965
[2]   NUCLEOTIDE-SEQUENCE OF A GENE FROM THE PSEUDOMONAS TRANSPOSON-TN501 ENCODING MERCURIC REDUCTASE [J].
BROWN, NL ;
FORD, SJ ;
PRIDMORE, RD ;
FRITZINGER, DC .
BIOCHEMISTRY, 1983, 22 (17) :4089-4095
[3]  
CARTER P, 1985, OLIGONUCLEOTIDE SITE
[4]  
Cleland W W, 1979, Methods Enzymol, V63, P103
[5]   FLAVIN BINDING-SITE DIFFERENCES BETWEEN LIPOAMIDE DEHYDROGENASE AND GLUTATHIONE-REDUCTASE AS REVEALED BY STATIC AND TIME-RESOLVED FLAVIN FLUORESCENCE [J].
DEKOK, A ;
VISSER, AJWG .
FEBS LETTERS, 1987, 218 (01) :135-138
[6]   MERCURIC REDUCTASE - HOMOLOGY TO GLUTATHIONE-REDUCTASE AND LIPOAMIDE DEHYDROGENASE - IODOACETAMIDE ALKYLATION AND SEQUENCE OF THE ACTIVE-SITE PEPTIDE [J].
FOX, BS ;
WALSH, CT .
BIOCHEMISTRY, 1983, 22 (17) :4082-4088
[7]   GLUTATHIONE-REDUCTASE FROM ESCHERICHIA-COLI - CLONING AND SEQUENCE-ANALYSIS OF THE GENE AND RELATIONSHIP TO OTHER FLAVOPROTEIN DISULFIDE OXIDOREDUCTASES [J].
GREER, S ;
PERHAM, RN .
BIOCHEMISTRY, 1986, 25 (09) :2736-2742
[8]   THIOREDOXIN [J].
HOLMGREN, A .
ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 :237-271
[9]   KINETICS OF REVERSE REACTION CATALYZED BY GLUTATHIONE REDUCTASE OF YEAST [J].
ICEN, AL .
FEBS LETTERS, 1971, 16 (01) :29-+
[10]   REFINED STRUCTURE OF GLUTATHIONE-REDUCTASE AT 1.54 A RESOLUTION [J].
KARPLUS, PA ;
SCHULZ, GE .
JOURNAL OF MOLECULAR BIOLOGY, 1987, 195 (03) :701-729
1234