NEURODEVELOPMENTAL OUTCOME OF CHILDREN WITH EVIDENCE OF PERIVENTRICULAR LEUKOMALACIA ON LATE MRI

被引:42
作者
FELDMAN, HM
SCHER, MS
KEMP, SS
机构
[1] Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA
[2] Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA
关键词
D O I
10.1016/0887-8994(90)90020-2
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Fifteen children, 8 months of age or older, from a neonatal follow-up program underwent magnetic resonance imaging and neurologic, cognitive, and language evaluations. Magnetic resonance imaging findings in all children included increased white matter signal on T2-weighted images and ventricular enlargement adjacent to regions of abnormal white matter. The extent and degree of abnormal white matter signal and the degree of sulcal prominence were variable. Twelve children had cerebral palsy; 5 children, 4 of whom had cerebral palsy, manifested significant sensory impairments. The median score on cognitive testing was 89; only 2 children exhibited severe-to-profound cognitive disability. Cognitive scores were stable on retesting. The degree of motor disability was correlated with the extent of white matter signal abnormality; however, cognitive outcome was not related to the extent and degree of white matter signal abnormality or to the degree of sulcal prominence. Despite the association of a major handicapping condition and periventricular leukomalacia, cognitive and language functioning may be relatively spared. © 1990.
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页码:296 / 302
页数:7
相关论文
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