Posterior reversible encephalopathy syndrome in pediatric acute leukemia: Case series and literature review

被引：7

作者：

Appachu, Sandhya M. ^{[1
]}

Purohit, Samit ^{[1
]}

Lakshmaiah, K. C. ^{[1
]}

Kumari, Aruna B. S. ^{[2
]}

Appaji, L. ^{[2
]}

机构：

[1] Kidwai Mem Inst Oncol, Dept Med Oncol, Bangalore, Karnataka, India

[2] Kidwai Mem Inst Oncol, Dept Pediat Oncol, Bangalore, Karnataka, India

来源：

INDIAN JOURNAL OF MEDICAL AND PAEDIATRIC ONCOLOGY | 2014年 / 35卷 / 01期

关键词：

Encephalopathy syndrome; PRES; steroid induced encephalopathy;

D O I：

10.4103/0971-5851.133727

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state coupled with a unique radio imaging appearance. We describe this rare, mostly reversible condition in five cases undergoing similar treatment under preset protocol (MCP-841) for acute lymphoblastic leukemia (ALL) at our centre. Hypertension is a well-known adverse effect of high-dose corticosteroid therapy primarily mediated by its effects on the mineralocorticoid receptor especially in pediatric population and we hypothesize that this may be the etiology of PRES in two of these patients.

引用

页码：79 / 82

页数：4

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