ACTIVITY OF SOLUBLE FACTORS PRODUCED BY EPSTEIN-BARR VIRUS-TRANSFORMED HUMAN LYMPHOCYTES-B ON DIFFERENT CELL-LINES

被引：1
|
作者：
GARZELLI, C
BAZZICHI, A
机构：
[1] Department of Biomedicine, Section of Microbiology, University of Pisa, Pisa, I-56 100
来源：
EXPERIENTIA | 1991年 / 47卷 / 07期
关键词：
EPSTEIN-BARR VIRUS; GROWTH FACTORS; CELL LINES;
D O I：
10.1007/BF01958829
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Self-stimulatory growth factors, produced by a human Epstein-Barr virus (EBV)-positive lymphoblastoid B cell line, named BA-D10-4, have been tested for the capacity to induce DNA synthesis in various human and animal cell lines, including lymphoid, either EBV-positive or EBV-negative, and non-lymphoid cell lines. It has been found that BA-DIO-4 cells produce growth factors which seem to be essential for their sustained proliferation in vitro, and which increase DNA synthesis in different primate lymphoid cells, independently of the presence of the EBV genome and of the lymphocyte lineage.
引用
收藏
页码：731 / 734
页数：4
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