REACTIONS OF FLUOROBENZENE TRICARBONYLCHROMIUM COMPLEXES WITH ANIONS FROM SCHIFF-BASES OF ALPHA-AMINO ESTERS - ENANTIOSELECTIVE SYNTHESIS OF ALPHA-ARYL AMINO-ACIDS

被引：34

作者：

CHAARI, M ^{[1
]}

JENHI, A ^{[1
]}

LAVERGNE, JP ^{[1
]}

VIALLEFONT, P ^{[1
]}

机构：

[1] UNIV MONTPELLIER 2,SYNTH & ETUD PHYSICOCHIM AMINOACIDES & PEPTIDES LAB,URA 468,PLACE E BATAILLON,F-34095 MONTPELLIER 5,FRANCE

来源：

TETRAHEDRON | 1991年 / 47卷 / 26期

关键词：

D O I：

10.1016/S0040-4020(01)86468-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report here a convenient synthesis of alpha-substituted aryl amino acids via the addition of alpha-imino esters to fluorobenzene tricarbonylchromium complexes. Optically pure alpha-aryl amino acids have been prepared by enantioselective substitution of fluorobenzene complexes using Schiff bases of L-alanine, leucine and valine methyl esters and (1R, 2R, 5R)-2-hydroxypinan-3-one.

引用

页码：4619 / 4630

页数：12

共 30 条

[1]

ACHIWA K, 1970, Chemical and Pharmaceutical Bulletin (Tokyo), V18, P61

[2]

BAJGIJLL MJ, 1978, OMIUAHEDRON LETT, V19, P4625

[3] ASYMMETRIC-SYNTHESIS OF ALPHA-DISUBSTITUTED AMINO-ACIDS [J].