MEMBRANE LIPID-PEROXIDATION BY ULTRASOUND - MECHANISM AND IMPLICATIONS

被引：17

作者：

JANA, AK ^{[1
]}

AGARWAL, S ^{[1
]}

CHATTERJEE, SN ^{[1
]}

机构：

[1] SAHA INST NUCL PHYS,DIV BIOPHYS,37 BELGACHIA RD,CALCUTTA 700037,INDIA

来源：

JOURNAL OF BIOSCIENCES | 1990年 / 15卷 / 03期

关键词：

hydroxyl radicals; lipid peroxidation; liposomes; scavengers; Ultrasound;

D O I：

10.1007/BF02703887

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Ultrasonic radiation produced a dose-dependent linear increase in lipid peroxidation in the liposomes membrane as reflected in the measurement of conjugated dienes, lipid hydroperoxides and malondialdehydes. Ultrasound induced malondialdehyde production could not be inhibited by any significant degree by superoxide dismutase or histidine or dimethyl furan but was very significantly inhibited by butylated hydroxytoluene, cholesterol, sodium benzoate, dimethyl sulphoxide, sodium formate and EDTA. The scavenger studies indicated the functional role of hydroxyl radicals in the initiation of ultrasound induced lipid peroxidation. © 1990 Indian Academy of Sciences.

引用

页码：211 / 215

页数：5

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