IN-UTERO TREATMENT OF FETAL GOITROUS HYPOTHYROIDISM CAUSED BY MATERNAL GRAVES-DISEASE

被引:8
|
作者
HADI, HA [1 ]
STRICKLAND, D [1 ]
机构
[1] E CAROLINA UNIV,SCH MED,DEPT OBSTET & GYNECOL,DIV MATERNAL FETAL MED,GREENVILLE,NC
关键词
GRAVES DISEASE; FETAL GOITROUS HYPOTHYROIDISM; THYROXINE; CARDOCENTESIS;
D O I
10.1055/s-2007-994520
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
We present two cases of maternal Craves' disease complicated by fetal goitrous hypothyroidism. Both patients had elevated maternal thyroid-stimulating immunoglobulin and thyrotropic-binding inhibitory immunoglobulin antibody titers. Diagnosis of fetal hypothyroidism was made by cordocentesis, and serial injections of thyroxine into the amniotic fluid resulted in return to normal of fetal thyroid size and function at birth. Significance of in utero management of fetal hypothyroidism is discussed.
引用
收藏
页码:455 / 458
页数:4
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