CELLULAR AND BEHAVIORAL NEUROBIOLOGY OF ALCOHOL - RECEPTOR-MEDIATED NEURONAL PROCESSES

被引：0
|
作者：
GRANT, KA [1 ]
LOVINGER, DM [1 ]
机构：
[1] WAKE FOREST UNIV, BOWMAN GRAY SCH MED, DEPT COMPARAT MED, WINSTON SALEM, NC 27157 USA
来源：
CLINICAL NEUROSCIENCE | 1995年 / 3卷 / 03期
关键词：
ETHANOL; GABA(A); NMDA; INOTROPIC RECEPTORS; RECEPTOR MECHANISMS;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Ethanol can be viewed as a receptor modulator, selectively altering neurochemical processes in discrete regions of the CNS. The actions of ethanol at two inotropic receptor systems, gamma-aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) glutamate receptors, are highlighted in this review. In addition, evidence is presented and discussed concerning the possible effects of ethanol that arise from interactions between these two receptor systems, the interactions of ethanol with phosphorylation states of receptor proteins and with metabotropic receptor systems. (C) 1995 Wiley-Liss, Inc.
引用
收藏
页码：155 / 164
页数：10
相关论文
共 50 条
  • [41] Crocin antagonizes ethanol inhibition of NMDA receptor-mediated responses in rat hippocampal neurons
    Abe, K
    Sugiura, M
    Shoyama, Y
    Saito, H
    BRAIN RESEARCH, 1998, 787 (01) : 132 - 138
  • [42] Ethanol inhibition of kainate receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala
    Lack, A. K.
    Ariwodola, O. J.
    Chappell, A. M.
    Weiner, J. L.
    McCool, B. A.
    NEUROPHARMACOLOGY, 2008, 55 (05) : 661 - 668
  • [43] NMDA receptor-mediated subthreshold Ca2+ signals in spines of hippocampal neurons
    Kovalchuk, Y
    Eilers, J
    Lisman, J
    Konnerth, A
    JOURNAL OF NEUROSCIENCE, 2000, 20 (05): : 1791 - 1799
  • [44] α7 Nicotinic acetylcholine receptor-mediated protection against ethanol-induced neurotoxicity
    de Fiebre, NC
    de Fiebre, CM
    ALCOHOL, 2003, 31 (03) : 149 - 153
  • [45] NMDA receptor-mediated pilocarpine-induced seizures: Characterization in freely moving rats by microdialysis
    Smolders, I
    Khan, GM
    Manil, J
    Ebinger, G
    Michotte, Y
    BRITISH JOURNAL OF PHARMACOLOGY, 1997, 121 (06) : 1171 - 1179
  • [46] ETHANOL INHIBITS EPILEPTIFORM ACTIVITY AND NMDA RECEPTOR-MEDIATED SYNAPTIC TRANSMISSION IN RAT AMYGDALOID SLICES
    GEAN, PW
    BRAIN RESEARCH BULLETIN, 1992, 28 (03) : 417 - 421
  • [47] Role of endothelial adenosine receptor-mediated vasorelaxation in ethanol-induced hypotension in hypertensive rats
    Rekik, M
    Ei-Mas, MM
    Mustafa, JS
    Abdel-Rahman, AA
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2002, 452 (02) : 205 - 214
  • [48] GLUTAMATE RECEPTOR-MEDIATED CALCIUM SURGES IN NEURONS DERIVED FROM P19 CELLS
    MORLEY, P
    MACPHERSON, P
    WHITFIELD, JF
    HARRIS, EW
    MCBURNEY, MW
    JOURNAL OF NEUROCHEMISTRY, 1995, 65 (03) : 1093 - 1099
  • [49] Ethanol inhibits muscarinic receptor-mediated DNA synthesis and signal transduction in human fetal astrocytes
    Guizzetti, M
    Möller, T
    Costa, LG
    NEUROSCIENCE LETTERS, 2003, 344 (01) : 68 - 70
  • [50] NMDA receptor-mediated extracellular adenosine accumulation is blocked by phosphatase 1/2A inhibitors
    Lu, Yin
    Rosenberg, Paul A.
    BRAIN RESEARCH, 2007, 1155 : 116 - 124
12345