CELLULAR AND BEHAVIORAL NEUROBIOLOGY OF ALCOHOL - RECEPTOR-MEDIATED NEURONAL PROCESSES

被引:0
|
作者
GRANT, KA [1 ]
LOVINGER, DM [1 ]
机构
[1] WAKE FOREST UNIV, BOWMAN GRAY SCH MED, DEPT COMPARAT MED, WINSTON SALEM, NC 27157 USA
关键词
ETHANOL; GABA(A); NMDA; INOTROPIC RECEPTORS; RECEPTOR MECHANISMS;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Ethanol can be viewed as a receptor modulator, selectively altering neurochemical processes in discrete regions of the CNS. The actions of ethanol at two inotropic receptor systems, gamma-aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) glutamate receptors, are highlighted in this review. In addition, evidence is presented and discussed concerning the possible effects of ethanol that arise from interactions between these two receptor systems, the interactions of ethanol with phosphorylation states of receptor proteins and with metabotropic receptor systems. (C) 1995 Wiley-Liss, Inc.
引用
收藏
页码:155 / 164
页数:10
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