ASYMMETRIC-SYNTHESIS OF A KEY CAMPTOTHECIN INTERMEDIATE FROM 2-FLUOROPYRIDINE

被引：1

作者：

COMINS, DL

SAHA, JK

机构：

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 44期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The DE ring camptothecin intermediate II was prepared enantioselectively in six steps from 2-fluoropyridine using a pyridine ''halogen-dance'' reaction.

引用

页码：7995 / 7998

页数：4

共 32 条

[1] Cai J-C., 1983, ALKALOIDS CHEM PHARM, VVol. 21, P101
[2] CIA JC, 1983, CHEM HETEROCYCL COMP, V25, P753
[3] A 6-STEP SYNTHESIS OF (+/-)-CAMPTOTHECIN
COMINS, DL
HONG, H
SAHA, JK
GAO, JH
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (18) : 5120 - 5121
[4] A 10-STEP, ASYMMETRIC-SYNTHESIS OF (S)-CAMPTOTHECIN
COMINS, DL
BAEVSKY, MF
HONG, H
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (27) : 10971 - 10972
[5] ASYMMETRIC-SYNTHESIS OF CAMPTOTHECIN ALKALOIDS - A 9-STEP SYNTHESIS OF (S)-CAMPTOTHECIN
COMINS, DL
HONG, H
JIANHUA, G
[J]. TETRAHEDRON LETTERS, 1994, 35 (30) : 5331 - 5334
[6] EFFICIENT SYNTHESIS AND RESOLUTION OF TRANS-2-(1-ARYL-1-METHYLETHYL)CYCLOHEXANOLS - PRACTICAL ALTERNATIVES TO 8-PHENYLMENTHOL
COMINS, DL
SALVADOR, JM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (17) : 4656 - 4661
[7] AN EFFICIENT PREPARATION OF (+)-TRANS-2-(ALPHA-CUMYL)CYCLOHEXANOL ((+)-TCC) - A PRACTICAL ALTERNATIVE TO (+)-8-PHENYLMENTHOL
COMINS, DL
SALVADOR, JM
[J]. TETRAHEDRON LETTERS, 1993, 34 (05) : 801 - 804
[8] COMINS DL, 1994, Patent No. 5315007
[9] COMINS DL, 1993, Patent No. 5254690
[10] COMINS DL, 1994, Patent No. 5321140

← 1 2 3 4 →