MAGNETIC-RESONANCE-IMAGING OF BODY-FAT OF ATHLETES COMPARED WITH CONTROLS, AND THE OXIDATIVE-METABOLISM OF ESTRADIOL

被引：13

作者：

FRISCH, RE

SNOW, R

GERARD, EL

JOHNSON, L

KENNEDY, D

BARBIERI, R

ROSEN, BR

机构：

[1] MASSACHUSETTS GEN HOSP E,NMR IMAGING CTR,BOSTON,MA

[2] MASSACHUSETTS GEN HOSP E,CTR NEUROSCI,BOSTON,MA

[3] BRIGHAM & WOMENS HOSP,DEPT OBSTET & GYNECOL,BOSTON,MA 02115

[4] HARVARD UNIV,SCH PUBL HLTH,DEPT POPULAT SCI,BOSTON,MA 02115

[5] MASSACHUSETTS GEN HOSP,DEPT RADIOL,BOSTON,MA 02114

来源：

METABOLISM-CLINICAL AND EXPERIMENTAL | 1992年 / 41卷 / 02期

关键词：

D O I：

10.1016/0026-0495(92)90151-Y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The extent of 2-hydroxylation of estradiol (E2), which yields a non-estrogenic metabolite (2-OHE1), increased significantly with decreasing subcutaneous fat (ScF)/total volume percent (TV%) and total fat (TF) TV% evaluated by magnetic resonance imaging (MRI) for five athletes during low- and high-intensity training, and four controls. The increase in 2-hydroxylation with decreasing adiposity was associated with anovulation and amenorrhea among the athletes. © 1992.

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页码：191 / 193

页数：3

相关论文

共 10 条

[1] RADIOMETRIC ANALYSIS OF BIOLOGICAL OXIDATIONS IN MAN - SEX-DIFFERENCES IN ESTRADIOL METABOLISM [J].

FISHMAN, J ;

BRADLOW, HL ;

SCHNEIDER, J ;

ANDERSON, KE ;

KAPPAS, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (08) :4957-4960

[2] INFLUENCE OF BODY-WEIGHT ON ESTRADIOL METABOLISM IN YOUNG-WOMEN [J].

FISHMAN, J ;

BOYAR, RM ;

HELLMAN, L .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1975, 41 (05) :989-991

[3] LOWER PREVALENCE OF BREAST-CANCER AND CANCERS OF THE REPRODUCTIVE-SYSTEM AMONG FORMER COLLEGE ATHLETES COMPARED TO NON-ATHLETES [J].

FRISCH, RE ;

WYSHAK, G ;

ALBRIGHT, NL ;

ALBRIGHT, TE ;

SCHIFF, I ;

JONES, KP ;

WITSCHI, J ;

SHIANG, E ;

KOFF, E ;

MARGUGLIO, M .

BRITISH JOURNAL OF CANCER, 1985, 52 (06) :885-891

[4] OVERALL BODY-FAT AND REGIONAL FAT DISTRIBUTION IN YOUNG-WOMEN - QUANTIFICATION WITH MR IMAGING [J].

GERARD, EL ;

SNOW, RC ;

KENNEDY, DN ;

FRISCH, RE ;

GUIMARAES, AR ;

BARBIERI, RL ;

SORENSEN, AG ;

EGGLIN, TK ;

ROSEN, BR .

AMERICAN JOURNAL OF ROENTGENOLOGY, 1991, 157 (01) :99-104

[5] IMPACT OF CONTINUOUSLY ADMINISTERED CATECHOL ESTROGENS ON UTERINE GROWTH AND LUTEINIZING-HORMONE SECRETION [J].

MARTUCCI, CP ;

FISHMAN, J .

ENDOCRINOLOGY, 1979, 105 (06) :1288-1292

[6] INDUCTION OF ESTRADIOL METABOLISM BY DIETARY INDOLE-3-CARBINOL IN HUMANS [J].

MICHNOVICZ, JJ ;

BRADLOW, HL .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1990, 82 (11) :947-949

[7] EFFECTS OF OBESITY ON ESTRADIOL METABOLISM - DECREASED FORMATION OF NONUTEROTROPIC METABOLITES [J].

SCHNEIDER, J ;

BRADLOW, HL ;

STRAIN, G ;

LEVIN, J ;

ANDERSON, K ;

FISHMAN, J .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1983, 56 (05) :973-978

[8]

SIITERI PK, 1981, J ENDOCRINOL, V89, pP119

[9] ESTROGEN 2-HYDROXYLASE OXIDATION AND MENSTRUAL FUNCTION AMONG ELITE OARSWOMEN [J].

SNOW, RC ;

BARBIERI, RL ;

FRISCH, RE .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1989, 69 (02) :369-376

[10] HYPOTHALAMIC DYSFUNCTION IN SECONDARY AMENORRHEA ASSOCIATED WITH SIMPLE WEIGHT-LOSS [J].

VIGERSKY, RA ;

ANDERSEN, AE ;

THOMPSON, RH ;

LORIAUX, DL .

NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (21) :1141-1145