CORTICOTROPIN RELEASE - INHIBITION BY INTRAHYPOTHALAMIC IMPLANTATION OF ATROPINE

被引：128
作者：
HEDGE, GA
SMELIK, PG
机构：
[1] Department of Pharmacology, Medical Faculty, University of Utrecht, Utrecht
来源：
SCIENCE | 1968年 / 159卷 / 3817期
关键词：
D O I：
10.1126/science.159.3817.891
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Anterior hypothalamic implantations of crystalline atropine markedly inhibit the adrenocortical responses evoked by surgical stress, ether anesthesia, or intravenous injection of arginine vasopressin. Similar implants in nearby regions of the brain or sham implantations in the same region were ineffective. The data suggest that the hypothalamic control of pituitary corticotropin may have a cholinergic component.
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页码：891 / &
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