ENANTIOSELECTIVE DEPROTONATION OF CYCLOHEXENE OXIDE TO (R)-2-CYCLOHEXEN-1-OL

被引：29

作者：

BHUNIYA, D ^{[1
]}

SINGH, VK ^{[1
]}

机构：

[1] INDIAN INST TECHNOL,DEPT CHEM,KANPUR 208016,UTTAR PRADESH,INDIA

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 10期

关键词：

D O I：

10.1080/00397919408011752

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of cyclohexene oxide with homochiral lithium amides, prepared from (S)-phenylglycine and (S)-valine has been studied and (R)-2-cyclohexen-1-ol 3 was prepared in a maximum of 72% ee. The optical purity was determined by H-1 NMR measurement of the alpha-methoxy-alpha-(trifluoromethyl)phenyl acetic acid (MTPA) derivative of the corresponding alcohol.

引用

页码：1475 / 1481

页数：7

共 13 条

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