SYNTHESIS OF 3-GEM-DIFLUORO-2-ETHOXY ALLYLIC ALCOHOLS FROM ETHYL CHLORODIFLUOROACETATE

被引：15

作者：

BEGUE, JP ^{[1
]}

BONNETDELPON, D ^{[1
]}

ROCK, MH ^{[1
]}

机构：

[1] CNRS,BIOCIS,CTR ETUD PHARMACEUT,F-92296 CHATENAY MALABRY,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期

关键词：

ETHYLCHLORODIFLUOROACETATE; WITTIG REACTION; EPOXIDATION; GEM-DIFLUOROALLYLIC ALCOHOLS;

D O I：

10.1016/0040-4039(94)88085-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chlorine atom in chlorodifluoromethyl epoxy ethers is usually reactive towards butyllithium. This reactivity has been used to develop a consise synthesis of gem-difluoro2-ethoxy allylic alcohols from the commercially available ethylchlorodifluoroacetate.

引用

页码：6097 / 6100

页数：4

共 21 条

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