SYNTHESIS, CHARACTERIZATION, DNA-BINDING, PHOTOCLEAVAGE AND ANTIMICROBIAL STUDIES OF COMPLEX [Ru(4-ETHYL-PYRIDINE)(4)(DPPZ)](2+)

被引：1
作者：
Naishadham, Padmaja [1 ]
Satyanarayana, S. [1 ]
机构：
[1] Osmania Univ, Dept Chem, Hyderabad, Andhra Pradesh, India
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2013年 / 4卷 / 06期
关键词：
Ru(II) complex; 4 - Ethyl Pyridine; DNA; binding;
D O I：
10.13040/IJPSR.0975-232.4(6).2265-73
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The new Ru (II) complex [Ru(4-Et-py)(4)(dppz)](2+) (dppz = dipyrido phenazine) have been synthesized and characterized by different analytical techniques like elemental analysis, LC-MS, H-1 NMR, C-13 NMR. The interaction of this complex with calf thymus DNA has been explored by U.V. absorption spectroscopy, Fluorescence measurements, and viscosity measurements. Their photocleavage behavior towards pBR 322 and anti-bacterial properties of this complex was also investigated. The experimental results show that the complex binds with DNA by intercalation mode.
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收藏
页码：2265 / 2273
页数：9
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