PROGRESS IN AIDS VACCINE DEVELOPMENT

被引：8

作者：

JOHNSTON, MI

机构：

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 1995年 / 108卷 / 04期

关键词：

AIDS; HUMAN IMMUNODEFICIENCY VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS; VACCINE; IMMUNE RESPONSES; ANTIBODIES; CYTOTOXIC T CELLS; ENVELOPE;

D O I：

10.1159/000237173

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Because of a unique combination of challenges facing human immunodeficiency virus vaccine developers, a number of traditional and novel vaccine designs are being evaluated essentially in parallel. Monomeric proteins, poxvirus vectors, peptides, and particle-based candidate vaccines have entered or will soon enter human trials. Other designs are at earlier stages of development. All candidates evaluated to date in phase I/II human trials have proven safe and immunogenic. One or more of the most promising designs will soon progress to 'test of concept' clinical trials to determine efficacy.

引用

收藏

页码：313 / 317

页数：5

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