PROGRESS IN AIDS VACCINE DEVELOPMENT

被引：8
作者：
JOHNSTON, MI
机构：
来源：
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 1995年 / 108卷 / 04期
关键词：
AIDS; HUMAN IMMUNODEFICIENCY VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS; VACCINE; IMMUNE RESPONSES; ANTIBODIES; CYTOTOXIC T CELLS; ENVELOPE;
D O I：
10.1159/000237173
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Because of a unique combination of challenges facing human immunodeficiency virus vaccine developers, a number of traditional and novel vaccine designs are being evaluated essentially in parallel. Monomeric proteins, poxvirus vectors, peptides, and particle-based candidate vaccines have entered or will soon enter human trials. Other designs are at earlier stages of development. All candidates evaluated to date in phase I/II human trials have proven safe and immunogenic. One or more of the most promising designs will soon progress to 'test of concept' clinical trials to determine efficacy.
引用
收藏
页码：313 / 317
页数：5
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