A VERSATILE SYNTHESIS OF AMINO TRIFLUOROMETHYL KETONES AND ALCOHOLS

被引：37

作者：

BEGUE, JP ^{[1
]}

BONNETDELPON, D ^{[1
]}

SDASSI, H ^{[1
]}

机构：

[1] UNIV CHOUAIB,FAC SCI,EL JADIDA,MOROCCO

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 14期

关键词：

AMINO TRIFLUOROMETHYL KETONE; PROTEASE INHIBITOR; FLUORINATED EPOXIDE; AMINOALCOHOL; ENOL ETHER;

D O I：

10.1016/S0040-4039(00)74166-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short, selective and general route to alpha-amino trifluoromethyl ketones and corresponding alcohols is described via an easy epoxidation of 1-CF3 enol ethers followed by an opening with various secondary amines.

引用

页码：1879 / 1882

页数：4

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