DEPRESSION OF EXPERIMENTAL GASTRIC-ULCERS AND ACUTE-PANCREATITIS IN RATS TREATED BY 5-AZACYTOSINE, 5-AZACYTIDINE AND THEIR N-METHYL DERIVATIVES

被引：0

作者：

CIHAK, A ^{[1
]}

PISKALA, A ^{[1
]}

KORBOVA, L ^{[1
]}

CIZKOVA, J ^{[1
]}

KUCEROVA, V ^{[1
]}

机构：

[1] CHARLES UNIV, DEPT PATHOL PHYSIOL, PRAGUE 2, CZECHOSLOVAKIA

来源：

EXPERIENTIA | 1986年 / 42卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

5-Azacytosine, 1-methyl-5-azacytosine and 5-azacytidine administered to rats with a ligated pylorus block gastric secretion, gastric acidity, the extent of hemorrhage and the number and size of gastric defects. The same drugs also depress the development of experimental acute pancreatic mediated in rats by interstitial administration of 7.5% natrium cholate into the pancreas in vivo. The drugs affected the amount of abdominal fluid and 6 h after the treatment the pathological changes were significantly decreased.

引用

页码：32 / 33

页数：2

共 13 条

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