CHARACTERIZATION OF 2 HUMAN MAMMARY CARCINOMAS, MT-1 AND MT-3, SUITABLE FOR INVIVO TESTING OF ETHER LIPIDS AND THEIR DERIVATIVES

被引：42

作者：

NAUNDORF, H

REWASOWA, EC

FICHTNER, I

BUTTNER, B

BECKER, M

GORLICH, M

机构：

[1] MAX DELBRUCK CENTRUM MOLEC MED,BUCH,GERMANY

[2] ACAD MED SCI,CANC RES CTR,MOSCOW,USSR

来源：

BREAST CANCER RESEARCH AND TREATMENT | 1992年 / 23卷 / 1-2期

关键词：

EXPERIMENTAL CHEMOTHERAPY; ETHER LIPIDS; HUMAN MAMMARY CARCINOMA; NUDE MICE;

D O I：

10.1007/BF01831480

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The human mammary carcinomas MT-1 and MT-3 originate from surgical material and were transplanted in nude mice. Both tumors have been classified as estradiol- and progesterone receptor-negative. Therapeutic doses of hormones and anti-hormones remained without growth inhibitory effect. MT-1 and MT-3 proved to be sensitive to conventional cytostatic drugs used for treatment of mammary carcinomas; striking is their sensitivity to ether lipids. Therefore, they are considered suitable tumor models for this class of substances.

引用

页码：87 / 95

页数：9

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