PROSTAGLANDINS .4. SYNTHESIS OF (+/-)-11-DEOXYPROSTAGLANDINS FROM 2-(OMEGA-HYDROXYHEPTYL)CYCLOPENT-2-ENONES

被引：24

作者：

BURTON, TS ^{[1
]}

CATON, MPL ^{[1
]}

COFFEE, ECJ ^{[1
]}

PARKER, T ^{[1
]}

STUTTLE, KAJ ^{[1
]}

WATKINS, GL ^{[1
]}

机构：

[1] MAY & BAKER LTD, RES LABS, DAGENHAM RM10 7XS, ESSEX, ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1976年 / 23期

关键词：

D O I：

10.1039/p19760002550

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conjugate nitrile addition to 2-(7-hydroxyheptyl)cyclopent-2-enone and subsequent elaboration via some aldehydes affords a convenient direct route to (.+-.)-11-deoxyprostaglandins of the E1 and F1 series. Syntheses of (.+-.)-10-methyl- and (.+-.)-.alpha.-nor-11-deoxyprostaglandins are also described.

引用

页码：2550 / 2556

页数：7

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