HISTOCHEMICALLY DEMONSTRABLE PHOSPHOTYROSINE PROTEIN PHOSPHATASE IN THE RAT HIPPOCAMPAL-FORMATION

被引：6

作者：

YOSHIOKA, T

TANAKA, O

OTANI, H

SHINOHARA, H

机构：

[1] SHIMANE MED UNIV,DEPT ANAT,89-1 ENYA CHO,IZUMO,SHIMANE 693,JAPAN

[2] INST DEV RES,DEPT BIOCHEM,KASUGAI,AICHI 48003,JAPAN

来源：

BRAIN RESEARCH | 1991年 / 555卷 / 01期

关键词：

PROTEIN PHOSPHATASE; PHOSPHOTYROSINE; HISTOCHEMISTRY; HIPPOCAMPAL FORMATION; RAT;

D O I：

10.1016/0006-8993(91)90877-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Using omicron-phospho-L-tyrosine as substrate, a possible localization of phosphotyrosine protein phosphatase (PTPPase) activity was histochemically demonstrated in the rat hippocampal formation. The PTPPase activity was found in almost all layers of the hippocampal formation, with a high activity in the stratum moleculare. The activity was inhibited by vanadate and molybdate, but not by NaF Zn2+. The activity was localized in the dendritic cytoplasm, particularly on the postsynaptic density, of hippocampal neurons.

引用

页码：177 / 179

页数：3

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