MEIBOMIAN THERAPY IN PROBLEMATIC CONTACT-LENS WEAR

被引:49
作者
PAUGH, JR
KNAPP, LL
MARTINSON, JR
HOM, MM
机构
[1] Allergan Optical, Irvine, CA
[2] Oxnard, CA
[3] Minot, ND
[4] Southern California College of Optometry, Fullerton, CA
关键词
Contact lens intolerance; Meibomian gland dysfunction; Meibomian therapy; Tear film breakup time;
D O I
10.1097/00006324-199011000-00002
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Utilizing the principal diagnostic criterion of an absent or cloudy Meibomian gland secretion upon repeated expression, patients with Meibomian gland dysfunction (MGD) were selected to participate in a study of the efficacy of lid scrubs and massage in the treatment of MGD. Twenty-one patients with contact lens intolerance unrelated to lens, care system, or health factors were randomly assigned to treatment of one eye with common clinical therapy for MGD. After 2 weeks of treatment, gland expression, biomicroscopy, staining, comfort, and fluorescein breakup time were assessed in a masked manner. Analyzed using a paired-data t-test, the results indicated a significant increase in mean tear film breakup time (BUT) in the treated eye at followup compared to baseline (mean increase=4.0 s, p=0.0001). The control eye demonstrated no significant change (mean increase=0.2 s, p=0.5955). These objective results were corroborated by reports of improved subjective comfort with contact lens wear after therapy. © 1990 American Academy of Optometry.
引用
收藏
页码:803 / 806
页数:4
相关论文
共 12 条
  • [1] McCulley J.P., Sciallis G.F., Meibomian keratoconjunctivitis, Am J Ophthalmol, 84, pp. 788-793, (1977)
  • [2] McCulley J.P., Sciallis G.F., Meibomian keratoconjunctivitis: Oculo-dermal correlates, CLAO J, 9, pp. 130-132, (1983)
  • [3] McCulley J.P., Dougherty J.M., Blepharitis associated with acne rosacea and seborrheic dermatitis, Int Ophthalmol Clin, 25, pp. 159-172, (1985)
  • [4] McCulley J.P., Dougherty J.M., Deneau D.G., Classification of chronic blepharitis, Ophthalmology (Rochester), 89, pp. 1173-1189, (1982)
  • [5] Fienriquez A.S., Korb D.R., Meibomian glands and contact lens wear, Br J Ophthalmol, 65, pp. 108-111, (1981)
  • [6] Robin J.B., Nobe J.R., Suarez E., Jester J.V., Smith R.E., Meibomian gland evaluation in patients with extended wear soft contact lens deposits, CLAO J, 12, pp. 95-98, (1986)
  • [7] Gutgesell V.J., Stern G.A., Flood C.I., Flistopathology of meibomian gland dysfunction, Am J Ophthalmol, 94, pp. 383-387, (1982)
  • [8] McCulley J.P., Blepharoconjunctivitis, Int Ophthalmol Clin, 24, pp. 65-77, (1984)
  • [9] Paugh J.R., Flom M.M., Knapp L.L., Martinson J.R., The incidence of Meibomian gland dysfunction, Am J Optom Physiol Opt, 65, (1988)
  • [10] Osgood J.K., Dougherty J.M., McCulley J.P., The role of wax and sterol esters of Meibomian secretions in chronic blepharitis, Invest Ophthalmol Vis Sci, 30, pp. 1958-1961, (1989)