INDUCTION OF THE OXIDATIVE RESPONSE AND OF CONCANAVALIN-A-BINDING CAPACITY IN MATURING HUMAN U937 CELLS

被引：11

作者：

BALSINDE, J ^{[1
]}

MOLLINEDO, F ^{[1
]}

机构：

[1] CSIC,CTR INVEST BIOL,VELAZQUEZ 144,E-28006 MADRID,SPAIN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1990年 / 1052卷 / 01期

关键词：

(U937 cell line); Cell differentiation; Concanavalin A; Membrane glycoprotein; Superoxide anion;

D O I：

10.1016/0167-4889(90)90061-H

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Differentiation of U937 cells with phorbol myristate acetate (PMA) induces high stimulation by concanavalin A of the respiratory burst as well as an increase in concanavalin A-binding cell capacity. New concanavalin A-binding proteins are detected as differentiated U937 cells acquire their capacity to be activated by concanavalin A. We identified several concanavalin A-binding proteins, of molecular mass 30-200 kDa, in PMA-differentiated cells, but only some of them seem to be directly related to the concanavalin A effect on the respiratory burst. One of these candidates could be a glycoprotein with an apparent molecular mass of 140 kDa which behaved as a major concanavalin A-binding protein and is expressed on differentiated cells at the time these cells respond maximally to concanavalin A. © 1990.

引用

页码：90 / 95

页数：6

共 49 条

[1] MODULATION OF SYNOVIAL CELL PRODUCTS BY A FACTOR FROM A HUMAN CELL-LINE - LYMPHOCYTE-T INDUCTION OF A MONONUCLEAR CELL FACTOR [J].

AMENTO, EP ;

KURNICK, JT ;

EPSTEIN, A ;

KRANE, SM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (17) :5307-5311

[2] 1-ALPHA,25-DIHYDROXYVITAMIN-D3 INDUCES MATURATION OF THE HUMAN MONOCYTE CELL-LINE U937, AND, IN ASSOCIATION WITH A FACTOR FROM HUMAN LYMPHOCYTES-T, AUGMENTS PRODUCTION OF THE MONOKINE, MONONUCLEAR CELL FACTOR [J].

AMENTO, EP ;

BHALLA, AK ;

KURNICK, JT ;

KRADIN, RL ;

CLEMENS, TL ;

HOLICK, SA ;

HOLICK, MF ;

KRANE, SM .

JOURNAL OF CLINICAL INVESTIGATION, 1984, 73 (03) :731-739

[3] INDUCTION OF SYNTHESIS OF COMPONENTS OF THE HYDROGEN PEROXIDE-GENERATING OXIDASE DURING ACTIVATION OF THE HUMAN MONOCYTIC CELL-LINE U937 BY INTERFERON-GAMMA [J].

ANDREW, PW ;

ROBERTSON, AK ;

LOWRIE, DB ;

CROSS, AR ;

JONES, OTG .

BIOCHEMICAL JOURNAL, 1987, 248 (01) :281-283

[4] THE INTERACTION OF ETHANOL AND EXOGENOUS ARACHIDONIC-ACID IN THE GENERATION OF EXTRACELLULAR MESSENGERS BY MOUSE PERITONEAL-MACROPHAGES [J].

BALSINDE, J ;

SCHULLER, A ;

DIEZ, E .

BIOCHIMICA ET BIOPHYSICA ACTA, 1988, 970 (01) :83-89

[5] SPECIFIC ACTIVATION BY CONCANAVALIN-A OF THE SUPEROXIDE ANION GENERATION CAPACITY DURING U937 DIFFERENTIATION [J].

BALSINDE, J ;

MOLLINEDO, F .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 151 (02) :802-808

[6]

BLACKSHEAR PJ, 1985, J BIOL CHEM, V260, P3304

[7] REGULATION OF PROSTAGLANDIN SYNTHESIS AND OF SELECTIVE RELEASE OF LYSOSOMAL HYDROLASES BY MOUSE PERITONEAL MACROPHAGES [J].

BONNEY, RJ ;

WIGHTMAN, PD ;

DAVIES, P ;

SADOWSKI, SJ ;

KUEHL, FA ;

HUMES, JL .

BIOCHEMICAL JOURNAL, 1978, 176 (02) :433-442

[8]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[9] PROTEIN KINASE-C-MEDIATED NEGATIVE-FEEDBACK INHIBITION OF UNSTIMULATED AND BOMBESIN-STIMULATED POLYPHOSPHOINOSITIDE HYDROLYSIS IN SWISS-MOUSE 3T3 CELLS [J].

BROWN, KD ;

BLAKELEY, DM ;

HAMON, MH ;

LAURIE, MS ;

CORPS, AN .

BIOCHEMICAL JOURNAL, 1987, 245 (03) :631-639

[10] A MONOCLONAL-ANTIBODY TO CD11C ANTIGEN INHIBITS THE PRODUCTION OF SUPEROXIDE ANION INDUCED BY CONCANAVALIN-A IN PMA-DIFFERENTIATED U-937 CELLS [J].

CABANAS, C ;

LACAL, P ;

MOLLINEDO, F ;

LOPEZRIVAS, A ;

SANCHEZMADRID, F ;

BERNABEU, C .

IMMUNOLOGY LETTERS, 1989, 20 (03) :193-198

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