EVIDENCE FOR A THIOL REAGENT INHIBITING CHOLINE-ACETYLTRANSFERASE BY REACTING WITH THIOL-GROUP OF COENZYME-A FORMING A POTENT INHIBITOR

被引：19

作者：

CURRIER, SF ^{[1
]}

MAUTNER, HG ^{[1
]}

机构：

[1] TUFTS UNIV,SCH MED,DEPT BIOCHEM & PHARMACOL,BOSTON,MA 02111

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1976年 / 69卷 / 02期

关键词：

D O I：

10.1016/0006-291X(76)90540-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：431 / 436

页数：6

共 11 条

[1]

BERMANREISBERG R, 1954, BIOCHIM BIOPHYS ACTA, V14, P442

[2]

BERMANREISBERG RB, 1957, YALE J BIOL MED, V29, P403

[3] A COENZYME A ANALOGUE DESULPHO-COA - PREPARATION AND EFFECTS ON VARIOUS ENZYMES [J].

CHASE, JFA ;

MIDDLETO.B ;

TUBBS, PK .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1966, 23 (02) :208-&

[4] MECHANISM OF ACTION OF CHOLINE-ACETYLTRANSFERASE [J].

CURRIER, SF ;

MAUTNER, HG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (09) :3355-3358

[5] RAPID RADIOCHEMICAL METHOD FOR DETERMINATION OF CHOLINE-ACETYLTRANSFERASE [J].

FONNUM, F .

JOURNAL OF NEUROCHEMISTRY, 1975, 24 (02) :407-409

[6] PURIFICATION OF CHOLINE-ACETYLTRANSFERASE OF SQUID-HEAD GANGLIA [J].

HUSAIN, SS ;

MAUTNER, HG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (12) :3749-3753

[7] INHIBITION OF CHOLINE ACETYLTRANSFERASE FROM BOVINE CAUDATE NUCLEUS BY SULFHYDRYL REAGENTS AND REACTIVATION OF INHIBITED ENZYME [J].

MANNERVIK, B ;

SORBO, B .

BIOCHEMICAL PHARMACOLOGY, 1970, 19 (08) :2509-+

[8] The formation of acetylcholine. A new enzyme: "Choline acetylase" [J].

Nachmansohn, D ;

Machado, AL .

JOURNAL OF NEUROPHYSIOLOGY, 1943, 6 (5-6) :397-403

[9]

POTTER LT, 1968, J BIOL CHEM, V243, P3864

[10]

ROSKOSKI R, 1974, J BIOL CHEM, V249, P2156

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