Detection of Circulating Tumor Cells

被引:46
|
作者
de Wit, Sanne [1 ]
van Dalum, Guus [1 ]
Terstappen, Leon W. M. M. [1 ]
机构
[1] Univ Twente, MIRA Inst Biomed Technol & Tech Med, Fac Sci & Technol, Dept Med Cell BioPhys, Room C4437,Hallenweg 23, NL-7522 NH Enschede, Netherlands
来源
SCIENTIFICA | 2014年 / 2014卷
关键词
D O I
10.1155/2014/819362
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The increasing number of treatment options for patients with metastatic carcinomas has created an accompanying need for methods to determine if the tumor will be responsive to the intended therapy and to monitor its effectiveness. Ideally, these methods would be noninvasive and provide quantitative real-time analysis of tumor activity in a variety of carcinomas. Assessment of circulating tumor cells shed into the blood during metastasis may satisfy this need. Here we review the CellSearch technology used for the detection of circulating tumor cells and discuss potential future directions for improvements.
引用
收藏
页数:11
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