TOTAL SYNTHESIS OF THE POLYENE MACROLIDE ROXATICIN

被引:22
|
作者
MORI, Y
ASAI, M
KAWADE, J
OKUMURA, A
FURUKAWA, H
机构
[1] Faculty of Pharmacy, Meijo University, Tempaku-ku, Nagoya
关键词
D O I
10.1016/S0040-4039(00)78257-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Roxaticin has been synthesized in a convergent manner. The polyol and polyene fragments were coupled by Horner-Emmons reaction and the cyclization was achieved by macrolactonization.
引用
收藏
页码:6503 / 6506
页数:4
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