HLA-A AND HLA-B ANTIGENS IN CHRONIC-BRONCHITIS

被引:2
作者
ANAGNOSTOPOULOU, U [1 ]
TOUMBIS, M [1 ]
KONSTANTOPOULOS, K [1 ]
KOTSOVOULOUFOUSKAKI, V [1 ]
ZERVAS, J [1 ]
机构
[1] UNIV ATHENS,LAIKON HOSP,DEPT MED 1,GR-11527 ATHENS,GREECE
关键词
CHRONIC BRONCHITIS; HLA ANTIGENS;
D O I
10.1016/0895-4356(93)90141-M
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
The A- and B- types of Human Leucocyte Antigens (HLA) were examined in a group of Greek patients with a diagnosis of chronic bronchitis. The results were compared to those of 400 healthy unrelated controls (smokers and non-smokers) from the same population. A statistically significant increase of HLA-A1 and HLA-B17 was noted; a similar increase was also noted when only healthy smokers were utilized as a control group. These results support the hypothesis that genetic factors are also involved in the pathogenesis of this common disease.
引用
收藏
页码:1413 / 1416
页数:4
相关论文
共 7 条
[1]  
CROFTON G, 1981, RESPIRATORY DISEASES
[2]  
FALING LJ, 1983, CLIN CHEST MED, V4, P377
[3]  
KHAITOVA NM, 1991, TERAPEVT ARKH, V63, P48
[4]   GENETIC AND ENVIRONMENTAL DETERMINANTS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE [J].
LARSON, RK ;
BARMAN, ML ;
KUEPPERS, F ;
FUDENBERG, HH .
ANNALS OF INTERNAL MEDICINE, 1970, 72 (05) :627-+
[5]  
MASSARO D, 1965, AM REV RESPIR DIS, V192, P94
[6]  
1962, AM REV RESPIR DIS, V85, P762
[7]  
1976, DHEW NIH75 PUBL, P22