Brimonidine purite solution for open-angle glaucoma or ocular hypertension

被引：0

作者：

Batiste, Corey G. ^{[2
,3
]}

Myers, Jonathan ^{[2
,3
]}

Katz, L. Jay ^{[1
,3
]}

机构：

[1] Wills Eye Hosp & Res Inst, Glaucoma Serv, Philadelphia, PA 19107 USA

[2] Wills Eye Hosp & Res Inst, Philadelphia, PA 19107 USA

[3] Thomas Jefferson Med Univ, Philadelphia, PA 19107 USA

来源：

EXPERT REVIEW OF OPHTHALMOLOGY | 2008年 / 3卷 / 05期

关键词：

brimonidine purite; ocular hypertension; open-angle glaucoma;

D O I：

10.1586/17469899.3.5.513

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Brimonidine (0.1 and 0.15%) tartrate used with the preservative purite has been shown to be as efficacious as brimonidine 0.2% tartrate in lowering intraocular pressure in clinical trials. The purite preservative has proven to be better tolerated and less toxic in brimonidine solution than the original preservative benzalkonium chloride. In addition, the lower concentrations of active drug appear to offer safer adverse event profiles than the original formulation, while maintaining its efficacy.

引用

页码：513 / 515

页数：3

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