Brimonidine purite solution for open-angle glaucoma or ocular hypertension

Brimonidine (0.1 and 0.15%) tartrate used with the preservative purite has been shown to be as efficacious as brimonidine 0.2% tartrate in lowering intraocular pressure in clinical trials. The purite preservative has proven to be better tolerated and less toxic in brimonidine solution than the original preservative benzalkonium chloride. In addition, the lower concentrations of active drug appear to offer safer adverse event profiles than the original formulation, while maintaining its efficacy.