CRINUM; AN ENDLESS SOURCE OF BIOACTIVE PRINCIPLES: A REVIEW. PART 1- CRINUM ALKALOIDS: LYCORINE-TYPE ALKALOIDS

被引：19

作者：

Refaat, John ^{[1
]}

Kamel, Mohamed S. ^{[1
]}

Ramadan, Mahmoud A. ^{[2
]}

Ali, Ahmed A. ^{[2
]}

机构：

[1] Minia Univ, Fac Pharm, Pharmacognosy Dept, Al Minya 61519, Egypt

[2] Assiut Univ, Fac Pharm, Pharmacognosy Dept, Assiut 71515, Egypt

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2012年 / 3卷 / 07期

关键词：

Alkaloids; Amaryllidaceae; Chemical constituents; Crinum; Lycorine;

D O I：

10.13040/IJPSR.0975-8232.3(7).1883-90

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Crinum is an important Amaryllidaceous plant thanks to the valuable biological and therapeutic activities of its chemical constituents, especially alkaloids. Many Crinum species have been commonly used in traditional medicines worldwide. Long ago, they have been subjected to extensive chemical, cytological and pharmacological investigations. Accordingly, this work comprehensively comprises both the alkaloidal and non-alkaloidal principles of Crinums isolated from 1950 and up to now, together with various biological and toxicological studies conducted on both the total extracts and individual compounds. As being a major common class of Crinum alkaloids, the current part of this review work highlights the lycorine-type alkaloids isolated so far from this plant in addition to their distribution in different Crinum species.

引用

页码：1883 / 1890

页数：8

共 8 条

[1] CRINUM; AN ENDLESS SOURCE OF BIOACTIVE PRINCIPLES: A REVIEW, PART II. CRINUM ALKALOIDS: CRININETYPE ALKALOIDS
Refaat, John
Kamel, Mohamed S.
Ramadan, Mahmoud A.
Ali, Ahmed A.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (09): : 3091 - +
[2] CRINUM; AN ENDLESS SOURCE OF BIOACTIVE PRINCIPLES: A REVIEW. PART III; CRINUM ALKALOIDS: BELLADINE-, GALANTHAMINE-, LYCORENINE-, TAZETTINE- TYPE ALKALOIDS AND OTHER MINOR TYPES
Refaat, John
Kamel, Mohamed S.
Ramadan, Mahmoud A.
Ali, Ahmed A.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2012, 3 (10): : 3630 - 3638
[3] CRINUM; AN ENDLESS SOURCE OF BIOACTIVE PRINCIPLES: A REVIEW. PART V. BIOLOGICAL PROFILE
Refaat, John
Kamel, Mohamed S.
Ramadan, Mahmoud A.
Ali, Ahmed A.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2013, 4 (04): : 1239 - 1252
[4] CRINUM; AN ENDLESS SOURCE OF BIOACTIVE PRINCIPLES: A REVIEW. PART IV: NON-ALKALOIDAL CONSTITUENTS
Refaat, John
Kamel, Mohamed S.
Ramadan, Mahmoud A.
Ali, Ahmed A.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2013, 4 (03): : 941 - 948
[5] Studies on the Crinum Alkaloids part Ⅱ[1]: Synthesis of Crinasiadine and Trisphaeridine
Hua Wu SHAO
Jun Chao CAI (Shanghai Institute of Nateria Medica
ChineseChemicalLetters, 1997, (06) : 493 - 496
[6] Bioactive potential and RP-HPLC detection of phenolics and alkaloids (lycorine and galanthamine) from ultrasonic-assisted extracts of Crinum roots
Lekhak, M. M.
Patel, S. B.
Otari, S. S.
Lekhak, U. M.
Ghane, S. G.
SOUTH AFRICAN JOURNAL OF BOTANY, 2022, 149 : 923 - 936
[7] SYNTHESIS OF LYCORINE-TYPE ALKALOIDS .1. 1-DESOXY-LYCORIN-7-ONE
TORSSELL, K
TETRAHEDRON LETTERS, 1974, (08) : 623 - 626
[8] Antioxidant, anti-diabetic, acetylcholinesterase inhibitory potential and estimation of alkaloids (lycorine and galanthamine) from Crinum species: An important source of anticancer and anti-Alzheimer drug
Ghane, S. G.
Attar, U. A.
Yadav, P. B.
Lekhak, M. M.
INDUSTRIAL CROPS AND PRODUCTS, 2018, 125 : 168 - 177

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